Glossary entry

Polish term or phrase:

jedno aminokwasowy nukleofil

English translation:

single amino acid nucleophile

Added to glossary by Jakub Rychter, PhD
Apr 2, 2015 09:16
9 yrs ago
Polish term

jedno aminokwasowy nukleofil

Polish to English Science Biology (-tech,-chem,micro-) Biotechnology
"... dodatek acetonitrylu (acetonitrile/DMF/H2O=8/1/1) zwiększał wydajność syntezy dla jedno aminokwasowych nukleofili (oprócz Gly-NH2) ..."
Proposed translations (English)
4 single amino acid nucleophile
Change log

Apr 9, 2015 12:56: Jakub Rychter, PhD Created KOG entry

Discussion

geopiet Apr 2, 2015:
single amino acid nucleophile?


All of the α-amino acids found in proteins (except glycine) are chiral at the α-carbon

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The α-carbons of 19 amino acids (all except for glycine) are “chiral” atoms.

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Most microorganisms such as E. coli can synthesize the entire basic set of 20 amino acids,

Proposed translations

6 days
Selected

single amino acid nucleophile

The observed selectivity for single amino acid substrates in acetonitrile for peptide synthesis was dramatically different than that observed for ester hydrolysis in aqueous solutions where no significant preference for single amino acid derivatives was apparent (Table 2).

https://books.google.es/books?id=ESxmF-ffqfkC&pg=PA333&dq=no...


The primary alcohol of serine and threonine as well as the thiol (–SH) of cysteine allow these amino acids to act as nucleophiles during enzymatic catalysis.


http://themedicalbiochemistrypage.org/amino-acids.php
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