Glossary entry (derived from question below)
Polish term or phrase:
jedno aminokwasowy nukleofil
English translation:
single amino acid nucleophile
Added to glossary by
Jakub Rychter, PhD
Apr 2, 2015 09:16
9 yrs ago
Polish term
jedno aminokwasowy nukleofil
Polish to English
Science
Biology (-tech,-chem,micro-)
Biotechnology
"... dodatek acetonitrylu (acetonitrile/DMF/H2O=8/1/1) zwiększał wydajność syntezy dla jedno aminokwasowych nukleofili (oprócz Gly-NH2) ..."
Proposed translations
(English)
4 | single amino acid nucleophile | Jakub Rychter, PhD |
Change log
Apr 9, 2015 12:56: Jakub Rychter, PhD Created KOG entry
Proposed translations
6 days
Selected
single amino acid nucleophile
The observed selectivity for single amino acid substrates in acetonitrile for peptide synthesis was dramatically different than that observed for ester hydrolysis in aqueous solutions where no significant preference for single amino acid derivatives was apparent (Table 2).
https://books.google.es/books?id=ESxmF-ffqfkC&pg=PA333&dq=no...
The primary alcohol of serine and threonine as well as the thiol (–SH) of cysteine allow these amino acids to act as nucleophiles during enzymatic catalysis.
http://themedicalbiochemistrypage.org/amino-acids.php
https://books.google.es/books?id=ESxmF-ffqfkC&pg=PA333&dq=no...
The primary alcohol of serine and threonine as well as the thiol (–SH) of cysteine allow these amino acids to act as nucleophiles during enzymatic catalysis.
http://themedicalbiochemistrypage.org/amino-acids.php
4 KudoZ points awarded for this answer.
Discussion
All of the α-amino acids found in proteins (except glycine) are chiral at the α-carbon
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The α-carbons of 19 amino acids (all except for glycine) are “chiral” atoms.
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Most microorganisms such as E. coli can synthesize the entire basic set of 20 amino acids,