Acuted-amphetamine administration to young rhesus monkeys (N=10) caused a motor syndrome of hypoactivity and chorea-like postures and motor movements which we have termed floating limb. Frequently after subcutaneous injections of 0.3 or 0.6 mg/kgd-amphetamine, an affected monkey raised one or both legs or arms and held the limb(s) motionless in the air. Affected limbs were usually returned to a normal position if they appeared to enter the animal's visual field. In other cases, the monkey assumed bizarre and contorted postures which were held for prolonged periods. Such postures were often accompanied by gentle repetitive brushing of the ears and facial hair with extremities of the affected limbs.
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