Glossary entry

English term or phrase:

osteotropic cytokine

Japanese translation:

骨吸収性サイトカイン

Added to glossary by Noriko Nevins
Jul 29, 2004 07:33
19 yrs ago
English term

osteotropic cytokine

English to Japanese Medical Medical (general)
Besides these proteins, a variety of local cytokines are involved in regulating osteoclast differentiation, and most of these osteotropic cytokines also affect the immune system, suggesting a strong relationship between these two systems.
Proposed translations (Japanese)
4 骨吸収性サイトカイン

Proposed translations

8 hrs
Selected

骨吸収性サイトカイン

「リウマチe-ネット、RAとImmunology、サイトカイン最前線」より
炎症部位で主に活性化マクロファージから産生されるサイトカインであるIL-1、IL-6、TNF-αは、破骨細胞性骨吸収の強い促進作用をもち、骨吸収性サイトカインとも呼ばれている。

The Journal of Immunology, 2002, 168: 5310-5317, "Inflammatory Microcrystals Alter the Functional Phenotype of Human Osteoblast-Like Cells In Vitro: Synergism with IL-1 to Overexpress Cyclooxygenase-2", Bouchard, et al.より
"In vitro, microcrystals strongly activate inflammatory cells such as monocytes-macrophages and neutrophils to express IL-1, a powerful osteotropic cytokine inducing bone resorption. "

osteo (骨の)+ tropic (向性や変化傾向を示す接尾語 ですから「骨吸収性サイトカイン」でよいのではないかと思います。
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3 KudoZ points awarded for this answer. Comment: "ありがとうございます。"
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