hipótesis colinérgica cholinergic hypothesis

Creator:	Luke Mersh
Language pair:	Da Spagnolo a Inglese
Discipline:	-
Definition / notes:	proposes that AD is caused by reduced synthesis of the neurotransmitter acetylcholine. The cholinergic hypothesis has not maintained widespread support, largely because medications intended to treat acetylcholine deficiency have not been very effective. Other cholinergic effects have also been proposed, for example, initiation of large-scale aggregation of amyloid,[49] leading to generalised neuroinflammation.[50]
URL:	http://en.wikipedia.org/wiki/Alzheimer%27s_disease