Glossary entry (derived from question below)
English term or phrase:
bioavailability
Danish translation:
biotilgængelighed
Nov 17, 2009 16:55
14 yrs ago
English term
bioavailability
GBK
English to Danish
Medical
Medical: Pharmaceuticals
Definition from
USC Kidney Transplant Program:
a measure of how much of an administered drug is absorbed into the bloodstream, actually reaching the intended site of action in the body. For example, medicine is absorbed from the GI tract, travels through the bloodstream, and reaches the organ tissues, where it works to fight infection, prevent rejection, etc.
Example sentences:
Differences in bioavailability among formulations of a given drug can have clinical significance; thus, knowing whether drug formulations are equivalent is essential. (Merck & Co., Inc. )
The term “relative bioavailability” refers to a comparison of two or more dosage forms in terms of their relative rate and extent of absorption. If an intravenous injection is employed as the reference dose, one can determine the absolute bioavailability of the test dosage form. (Informa plc )
Drug candidates can be tested for their desired therapeutic activity, but it is not yet possible to predict whether or not a compound will have sufficient bioavailability to be useful and practical. (US National Institutes of Health)
Proposed translations
(Danish)
5 +3 | biotilgængelighed | Alice Wolfe, DDS (X) |
5 | Biotilgængelighed | Niels Barfoed |
Change log
Nov 17, 2009 16:14: changed "Kudoz queue" from "In queue" to "Public"
Nov 17, 2009 16:55: changed "Stage" from "Preparation" to "Submission"
Nov 20, 2009 16:59: changed "Stage" from "Submission" to "Selection"
Nov 20, 2009 17:54: changed "Stage" from "Selection" to "Completion"
Proposed translations
+3
11 mins
Selected
biotilgængelighed
Definition from
Miljøordbog:
Hvor nemt et stof kan optages af levende organismer. Evnen til, at kemiske stoffer, der findes i sedimenter m.m., kan optages i og/eller påvirke levende organismer.
Example sentences:
Når disse informationer lægges ind i et biosimuleringsprogram, som også indeholder informationer om andre faktorers indflydelse på absorption og biotilgængelighed, kan man forhåbentlig i fremtiden udvikle mere sikre lægemiddelstoffer både hurtigere og billigere, end man kan i dag. (University of Copenhagen, Dept. of Pharm)
4 KudoZ points awarded for this answer.
21 mins
Biotilgængelighed
Definition from
AarhusUniversity, National Env. Res. Ins:
biotilgængelighed (bioavailability) <br />Hvor nemt et stof kan optages af levende organismer.
Example sentences:
Et højt indhold af kostfiber reducerer biotilgængeligheden af digoxin med 16-32%. (INSTITUTE FOR RATIONAL PHARMACOTHERAPY)
Ved samtidig anvendelse af aktive substanser, hvis biotilgængelighed påvirkes af pH-værdien i mavesyren, kan omeprazol nedsætte (fx ketoconazol og itraconazol) eller øge (fx erythromycin, clarithromycin og roxithromycin) optagelsen af disse. (Danish MEdicines Agency)
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